Brand Name | Status | Last Update |
---|---|---|
horizant | New Drug Application | 2023-08-29 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | — | 7 | 1 | — | 8 |
Partial epilepsies | D004828 | EFO_0004263 | — | — | — | 2 | 2 | 2 | 6 |
Epilepsy | D004827 | EFO_0000474 | G40.9 | — | — | — | 2 | 1 | 3 |
Seizures | D012640 | — | G40.4 | — | — | 1 | 1 | — | 2 |
Renal insufficiency | D051437 | — | N19 | — | — | — | 2 | — | 2 |
Complex partial epilepsy | D017029 | EFO_1000877 | — | — | — | — | 1 | — | 1 |
Diabetic neuropathies | D003929 | EFO_1000783 | — | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 1 | — | 1 | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neuralgia | D009437 | EFO_0009430 | — | — | — | — | — | 1 | 1 |
Postherpetic neuralgia | D051474 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Gabapentin enacarbil |
INN | gabapentin enacarbil |
Description | Gabapentin enacarbil is a carbamate ester that is the N-[1-(isobutyryloxy)ethoxy]carbonyl derivative of [1-(aminomethyl)cyclohexyl]acetic acid. The prodrug for gabapentin, used for treatment of neuropathic pain and restless legs syndrome. It has a role as a prodrug, an anticonvulsant and a calcium channel blocker. It is a monocarboxylic acid, a carbamate ester, a carboxylic ester and an acetal. It is functionally related to a gamma-aminobutyric acid and a gabapentin. |
Classification | Small molecule |
Drug class | gabamimetics |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC(OC(=O)NCC1(CC(=O)O)CCCCC1)OC(=O)C(C)C |
PDB | — |
CAS-ID | 478296-72-9 |
RxCUI | — |
ChEMBL ID | CHEMBL1628502 |
ChEBI ID | 68840 |
PubChem CID | 9883933 |
DrugBank | — |
UNII ID | 75OCL1SPBQ (ChemIDplus, GSRS) |